Tuesday, October 13, 2009

Always read the Methods sections

Do you know how hard it is to find Flickr shots of people reading journal articles? We'll settle for cute, instead. From KOMUnews via CC

Two Good Reasons To Always Read the Methods Section of a Scientific Paper

Sure, you could skip straight to "Conclusions" and get your soundbite. But if you make a habit of avoiding "Methods and Materials" you will miss out on some classic moments of science humor---both intentional and otherwise.

In my summer reading, I came across two excellent examples...

1) Chicken Soup for the Scientist's Soul (And Lunch)
The Paper: "Chicken Soup Inhibits Neutrophil Chemotaxis In Vitro", in the October 2000 issue of the journal Chest. Authors: Barbara O. Rennard, BA, Ronald F. Ertl, BS, Gail L. Gossman, BS, Richard A. Robbins, MD, FCCP, and Stephen I. Rennard, MD, FCCP.
The Discovery: My friend Jeff, Ph.D., who works for a friendly Environmental Sciences department somewhere in the South, sent me a link to this paper, which attempts to establish a medical explanation for why your Grammy was always feeding you chicken soup at the slightest hint of a sniffle. The authors theorize that chicken soup may have some mild anti-inflammatory effects, which could account for its popularity as folk medicine. In fact, according to the paper, the idea of treating respiratory illness with chicken soup dates at least back to the 12th century C.E., when it was recommended by the Egyptian Jewish physician and philosopher Maimonides.
Which is kind of nifty.
And the team does find some evidence supporting their theory, at least in the lab, where they exposed white blood cells called neutrophils to varying concentrations of chicken soup. Neutrophils play an important role in inflammation and higher concentrations of soup seemed to block them from doing this. You can read the whole paper online.

The funny part? They included the actual chicken soup recipe used in the study under "Methods and Materials". Actual quote from the paper:

Traditional chicken soup was prepared according to a family recipe, which will be referred to as "Grandma's soup" (C. Fleischer; personal communication; 1970).

I haven't tried it yet, but I'm planning on making a batch sometime this fall. The paper says the recipe is "very highly regarded locally" (a claim they back up with a citation).

2) Weekend at Bernie's
The Paper: "Sexual conflict over the duration of copulation in Drosophila montana: why is longer better?", in the June 12, 2009 issue of BMC Evolutionary Biology. Authors: Dominique Mazzi, Jenni Kesäniemi, Anneli Hoikkala and Kirsten Klappert.
The Discovery: I wrote about this research for the National Geographic News Web site. The basic gist: Male D. montana flies get more of an evolutionary benefit from longer sex. Females, meanwhile, do better with a shorter session. The research proved that the female flies had adapted in ways that allowed them to counter males' ability to hold them still. Turns out, the ladies had more control over the length of sex than anyone previously thought.
In my initial interviews, author Kirsten Klappert explained that the team had "incapacitated" the female flies to see how long sex lasted when lady flies had no control. Naturally, my editor and I were curious as to just how this worked.

Apparently, it works best if you kill the female flies.

Rather than engaging in insect bondage, the Methods section clarified that the team had gassed female flies to death, propped them up so they appeared alive and interested in sex, and tricked the male flies into necrophilia.

And you thought being detail-oriented was boring.

Wednesday, July 29, 2009

Schizophrenic mother eats her baby

SAN ANTONIO (AP) — The warning signs were there. Otty Sanchez, a schizophrenic with a history of hospitalizations, wasn't taking medication and was depressed after her son's birth, the boy's father said. A simple request seemed to set her off, alarming him and his family.

Yet, the 33-year-old woman was staying in a house where she had access to samurai swords. Child welfare officials were never called.

Instead, Sanchez's troubles became apparent to authorities when they found her before dawn Sunday screaming that she had killed her baby. Her 3 1/2-week-old son was dismembered in a scene so gruesome that police were left shaken.

"Maybe we missed" warning signs, San Antonio Police Chief William McManus said. "I don't know."

FIND MORE STORIES IN: Andrea Yates | Dena Schlosser

Sanchez was released Tuesday from a hospital where she had been treated for self-inflicted cuts to her torso and an attempt to slice her own throat. The former home health care worker, charged with capital murder, was being held at Bexar County Jail on $1 million bond. Calls to relatives Tuesday were not immediately returned and it was not clear whether Sanchez had an attorney.

Authorities said Sanchez tried killing herself after butchering her newborn son, Scott Wesley Buchholz-Sanchez, with a steak knife and two swords while her sister and two nieces, ages 5 and 7, slept in another room.

Sanchez told police — who described a scene so horrifying that investigators could barely speak to one another — that the devil made her kill, mutilate and eat parts of her only child.

Scott W. Buchholz, the infant's father who met Sanchez six years ago while they were studying to be pharmacists assistants, said he isn't buying it. He said although his girlfriend had postpartum depression and told him a week before the killing that she was schizophrenic, she didn't appear unstable.

He wants prosecutors to pursue the death penalty.

"She killed my son. She should burn in hell," Buchholz, 33, told The Associated Press.

Otty Sanchez's medical history is muddled. A family member said Sanchez had been undergoing psychiatric treatment and that a hospital called looking for her several months ago. Gloria Sanchez, Otty's aunt, said her niece had been "in and out of a psychiatric ward."

In May 2008, Otty Sanchez's mother, Manuela Sanchez, called police after her daughter didn't return from a trip to Austin, saying she was concerned about her daughter's safety. Manuela Sanchez told police she suspected Otty was into drugs and specifically told police she wasn't suffering from any mental issues.

Buchholz, who is himself schizophrenic and takes six anti-psychotic and anti-convulsive medications, said Otty had postpartum depression and had been going to regular counseling sessions after the birth, but refused to take prescription medication for her depression. Still, he said she seemed fine.

"She seemed like a a very caring, loving mother. She held him, she breast fed him. She did everything for him that was nice," he said.

On July 20, Sanchez was taken to the hospital for depression and released less than a day later, Buchholz said. Sanchez told him that she was schizophrenic and was going to live with her parents and sister. Sanchez was arrested at her mother's house, where police found her and the dead infant.

Five days later, on Saturday, Sanchez brought "Baby Scotty" for a visit but stormed out after he asked for a copy of the birth certificate and other documents, Buchholz said. Buchholz called 911 to report that Sanchez stormed out and drove away with the infant without properly restraining him in the car, and deputies investigated it as a disturbance.

The deputy took a report but could do little else, said Bexar County Sheriff Chief Deputy Dale Bennett.

"If this guy had given us an indication that she had postpartum depression, or mental defects she was suffering from, we may have addressed it differently," he said.

Buchholz said he may have told the deputy Sanchez was depressed, but that he wasn't sure.

While schizophrenia generally develops in men in their late teens and early 20s, women tend to develop the illness, marked by abnormal impressions of reality, later in life.

Most new mothers suffer from postpartum blues as hormones shift after a pregnancy and they're fatigued handling a new baby. But as many as one-fifth suffer from the more serious postpartum depression, which includes symptoms like despair and failing to eat or sleep.

Postpartum psychosis is far rarer, affecting only about one woman in 1,000. Women with postpartum psychosis have delusions, frequently involving religious symbols and a desire to harm their newborn, said Richard Pesikoff, a psychiatry professor at the Baylor College of Medicine.

He testified in the second trial of Andrea Yates, the high-profile case of a Houston-area mother found not guilty by reason of insanity after drowning her five children. Similar to Sanchez's claim that the devil told her to kill her son, Yates told authorities Satan was inside of her and she was trying to save her children.

"The most common part of postpartum psychosis is the delusional thinking," said Pesikoff. "Often but not always, it encompasses some type of religious thought. God is telling you to do something. The devil is telling you to do something."

Women with schizophrenia and bipolar disorder are at particularly high risk for developing postpartum psychosis.

For women with schizophrenia who are not taking medication, the risk of developing psychosis is 50% or higher, said Lucy Puryear, another psychiatrist who was involved in the Yates case.

If a mother is diagnosed with psychosis, she should immediately be hospitalized and separated from the child, Puryear said.

Some psychiatrists will tell women with schizophrenia not to have children because of the high risks, but she said with medication and treatment, "it's possible to have a child and have a good outcome."

While Sanchez could face trial, other similar cases — including that of Yates and Dena Schlosser, a Plano woman who said she sliced off her baby's arms because she wanted to give the baby to God — have ended with juries finding the women not guilty by reason of insanity.

FULL STORY at: http://www.usatoday.com/news/nation/2009-07-28-decapitated-baby_N.htm?csp=34

Tuesday, July 28, 2009

The Washington Post: Dual Disorders Rarely Treated Properly

Dual Disorders Rarely Treated Properly

VIDEO
The parents of Danny Watt, who died in April 2008, describe their son's struggles with mental illness and the treatment they believe failed him.
Washington Post Staff Writer
Tuesday, July 28, 2009


Danny Watt once leapt from a moving train. He hurtled through the windshield of a rolling car. Got pummeled by drug dealers. Overdosed. Swallowed rat poison. Tried to hang himself.

In his tumultuous 21 years, Danny Watt danced with death in the most amazing, horrible ways. In the end, two college students spotted him facedown in the cold, murky water of the C&O Canal one afternoon in April 2008. The medical examiner said Danny had drowned.

It was an end that Danny's parents, Bobby and Mary Watt of Reston, had struggled to stave off for many years. But after refinancing their house three times to put their son in every substance abuse and mental health program imaginable, after going to countless meetings and hearings and hospitals and jails, after badgering every possible person in Fairfax County who might help them, they could not save Danny.

"We just went through so much for so long," said Mary Watt, breaking into tears. "We tried and tried for so many years, fighting, only to lose."

Danny Watt was a walking symbol of a phenomenon called co-occurring disorders, or dual diagnosis, which is estimated to affect 7 million adults in the United States. These people are both seriously mentally ill and abusing drugs or alcohol. About half of all adults who are seriously mentally ill are also thought to be addicted. The mental health community calls this "self-medication." The federal government estimates that 90 percent of people with co-occurring disorders do not get the treatment they need.

Danny's death shows how hard it can be to treat people with co-occurring disorders and why so many die young.

Full Story: http://www.washingtonpost.com/wp-dyn/content/article/2009/07/27/AR2009072702248.html

Monday, June 29, 2009

Jani's at the mercy of her mind

The parents of a 6-year-old schizophrenic search for help against daunting odds for a patient so young and a case so severe.
By Shari Roan
June 29, 2009




It's been a rough week. A few days ago, at UCLA's Resnick Neuropsychiatric Hospital, 6-year-old Jani toppled a food cart and was confined to her room. She slammed her head against the floor, opening a bloody cut that sent her into hysterics. Later, she kicked the hospital therapy dog.

Jani normally likes animals. But most of her animal friends -- cats, rats, dogs and birds -- are phantoms that only she can see. January Schofield has schizophrenia. Potent psychiatric drugs -- in doses that would stagger most adults -- seem to skip off her. She is among the rarest of the rare: a child seemingly born mentally ill.

She suffers from delusions, hallucinations and paroxysms of rage so severe that not even her parents feel safe. She's threatened to climb into an oven. She's kicked and tried to bite her little brother. "I'm Jani, and I have a cat named Emily 54," she says, by way of introduction. "And I'm Saturn-the-Rat's baby sitter."

FULL STORY

Monday, June 15, 2009

Do Your Research...(tsk tsk)

Spectacular Planet...

Mars: The Red Planet is about to be spectacular!

Mars


The Red Planet is about to be spectacular!


This month and next, Earth is catching up with Mars in an encounter that
will culminate in the closest approach between the two planets in
recorded history. The next time Mars may come this close is
in 2287. Due to the way Jupiter's gravity tugs on
Mars and perturbs its orbit, astronomers can only be
certain that Mars has not come this close to Earth
in the Last 5,000 years, but it may be as long as
60,000 years before it happens again.

The encounter will culminate on August 27th when
Mars comes to within 34,649,589 miles of Earth and
will be (next to the moon) the brightest object in
the night sky. It will attain a magnitude of -2.9
and will appear 25.11 arc seconds wide. At a modest
75-power magnification


Mars will look as large as the full moon to the naked eye
.
Mars will be easy to spot. At the
beginning of August it will rise in the east at 10p.m.

and reach its azimuth at about 3 a.m.

By the end of August when the two planets are
closest
, Mars will rise at nightfall and reach its
highest point in the sky at 12:30a.m. That's pretty
convenient to see something that no human being has
seen in recorded history. So, mark your calendar at
the beginning of August to see Mars grow
progressively brighter and brighter throughout the
month.



NO ONE ALIVE TODAY WILL EVER SEE THIS AGAIN

Thursday, June 11, 2009

Friday, May 15, 2009

Workers may be more productive if allowed to surf the Internet


A University of Melbourne study found that workers who engage in ‘Workplace Internet Leisure Browsing’ (WILB) are more productive than those who don’t. “People who do surf the Internet for fun at work - within a reasonable limit of less than 20% of their total time in the office - are more productive by about 9% than those who don’t,” the author says. This is because “short and unobtrusive breaks, such as a quick surf of the internet, enables the mind to rest itself, leading to a higher total net concentration for a days work, and as a result, increased productivity.”

Summary of study

Some CITS students and affiliates recently completed a chapter on the topic of destructive use of communication technologies in the workplace which includes a survey of similar research.

Flanagin, A. J., Pearce, K., & Bondad-Brown, B. (in press). The destructive potential of electronic communication technologies in organizations. In P. Lutgen-Sandvik & B. Davenport-Sypher (Eds.), The destructive side of organizational communication: Processes, consequences, and constructive ways of organizing. Mahwah, NJ: Routledge/LEA.

Wednesday, May 13, 2009

Wednesday’s Lunchtime Poll

Eight PRU Pirates were asked the question: How little do you think you could spend on food, in a week, and still consume pretty much everything you needed/wanted? [This includes groceries, dining out, beverages, and snacks]

Responses were given in the form of single estimates and ranges, and varied dramatically; the lowest estimate provided was $30 compared to the highest at $120.

On average, the Pirates collectively estimate being able to spend $72.50 on everything they consume over the course of an average week.

Thank you to everyone who participated!

Monday, May 4, 2009

Blue Lazers to cure Schizophrenia?

Blue Laser Could Lead to Autism Cure

Eric Bland, Discovery News

Triggering Brain Waves
Triggering Brain Waves | Discovery News Video

April 29, 2009 -- Lasers could one day cure, or at least aid in the search for drugs that treat diseases ranging from autism to schizophrenia, according to two new studies from the Massachusetts Institute of Technology and Stanford University and published in the online issue of the journal Nature.

A blue laser shined into a live mouse brain triggered gamma waves, which are a kind of brain wave necessary for concentration and cognition that people with autism and schizophrenia often lack.

"There are lots of theories about why [gamma wave oscillation] is impaired," said Li-Huei Tsai, a professor at MIT and a co-author on one of the Nature papers.

"This is the first proof that a specific set of neurons are responsible for gamma waves."


Whole story: http://dsc.discovery.com/news/2009/04/29/brain-autism-laser.html


Friday, March 20, 2009

Japanese "Suicide Forest"


http://www.cnn.com/2009/WORLD/asiapcf/03/19/suicide.forrest.japan/index.html?eref=rss_topstories

Monday, February 16, 2009

Saturday, January 31, 2009

Wednesday, January 28, 2009

A Dramaturgical Summary of Where You Live

http://www.youtube.com/watch?v=LsH9hs9rbKo&feature=related

Tuesday, January 27, 2009

Come share the love..........


Don't be bored on those cold snowy nights. Come and hang out with 13 amazing musicians doing their thing. This is a seriously a super group enjoy them in their infancy.
In peace,
R. Sean

Johnny Brendas.

Monday, January 26, 2009

Taking Facebook Relationship Status' to a Whole new Level...

http://www.switched.com/2009/01/23/man-kills-wife-for-changing-facebook-status-to-single/

Friday, January 23, 2009

The Science of Love



In his article, Larry Young breaks down the biology of sexual intimacy and human bonding....or lack thereof.

It's raised a lot of speculation to say the least. In particular, this New York Times article discussing the imminent potential to actually create a love potion, and the benefits of its antidote as well....

I find this so interesting!!

Monday, January 12, 2009

Restaurant Week 2009

http://www.centercityphila.org/life/RWRestaurants.php

Restaurant Week is Coming Up --- January 25-30, 2009!!